Craft BioSolutions · Modular fermentation
Bioreactors that grow with your product.
Develop your microbial process with Craft, prove repeatable batches, and build toward production you can operate yourself. We’re developing modular fermentation systems for unusual microbes and small production runs, with capacity added as demand grows.
Start small. Earn the factory.
A route to your own production
Prove the process.
Then add capacity.
Start with a paid study on your culture and a clear definition of success. Each stage should earn the next: usable results, repeatable batches, then a system your team can operate.
Answer the first manufacturing question.
Agree on success criteria, run controlled experiments, and receive a documented assessment of process fit, with samples where applicable.
Scope my study →Work toward repeatable batches.
Develop the process, evaluate larger modules, and define the operator workflow and downstream handoff. Progress depends on the results.
Discuss pilot requirements →Build toward production you own.
Our planned cabinets use process-qualified, single-use bags. After validation and agreed milestones, the aim is to transfer the process to your operators and add cabinets as demand grows.
Explore the planned system →Studies are scoped individually. Pilot modules and cabinets are in development; specifications, pricing and delivery are subject to qualification and an agreed proposal.
Who we are building for
Useful biology.
A practical place to make it.
Our focus is bioactives and biomass from non-model microbes: organisms with oxygen, shear, surface-growth or media requirements that need a different production environment.
Living cultures for real-world trials.
Evaluate viable-cell output, unusual media and smaller batches for product development and field work. Begin with the strain and the trial requirement.
Processes built around the organism.
Explore feeding, sampling, oxygen demand and culture handling for fungal inoculum and specialty enzyme processes.
Grow the properties that matter.
Bacterial cellulose and other microbial materials can depend on surface growth and cultivation conditions. Assess the process and the output together.
These are target applications. Suitability and performance are established through a strain-specific feasibility study.
Tell us about your manufacturing decision →The system
A breathing bag.
Capacity in steps.
Shallow, supported, single-use vessels exchange gas through their walls. Sensors and controllable pumps make each run visible and help define how a process should be operated.
- A gentler environment. An architecture designed around passive gas transfer and low-energy operation.
- A record of every run. Measurements and operating conditions help identify what worked and what to test next.
- A path to ownership. Develop the process, qualify the larger module, then add cabinets as demand is proven.
Planned 200 L beta cabinetConcept rendering. Eight 25 L bags per run is the design target. The operating system today is 2 L; larger modules remain in development.Evidence · October 2026
Working hardware.
Clear next proofs.
17 instrumented runs.
Two organisms.
Our 2 L fed-batch system has run E. coli and bacterial cellulose cultures. Early results are evidence for continued development, not a guarantee for another strain.
Cellulose on both film faces.
Cellulose growth against both walls supports oxygen transfer through the film. Direct oxygen-transfer measurements and larger-bag performance are next validation steps.
Sense, record and command.
Sensor logging, a shared operator view and software-commanded pump rates work today. Sensor-triggered feeding and automatic end-of-run reports are in development.
The central engineering milestone is preserving useful oxygen transfer, mixing and process performance from 2 L to 25 L, then demonstrating repeatability on customer processes.
Develop with Craft
Help shape the machine
your process needs.
We’re looking for teams with a defined microbial product, a real manufacturing decision and resources for development. Bring your operating requirements; we’ll agree on experiments, deliverables and the evidence needed for each next step.
Design input
Your feed strategy, sampling needs, site constraints and operator workflow help shape development.
A scoped engagement
Start with a fit discussion and a written proposal for paid work, success criteria and deliverables.
A conditional route to beta
Work toward operating your own qualified process, with beta access subject to validation and agreed milestones.
Government, resilience and point-of-need partnerships
We welcome funded development with organizations assessing fermentation where infrastructure, logistics and specialist operators are constrained. Discuss the intended output, operating environment and evidence required for deployment.
Discuss a point-of-need program →Longer-term research: space-based biomanufacturing
We are exploring shallow vessels, gas transfer and low-energy operation for unusual environments. Space applications remain ground-development research; no flight readiness is claimed.
Notes from the Edge
The thinking behind the systems.
Let’s talk about your process
What do you need
to make next?
Tell us your product category, intended batch size, timeline and the decision you need to make. We’ll start with a fit discussion, then define a written scope if there’s a useful study or partnership to pursue.
Please keep this first inquiry non-confidential. We’ll arrange the appropriate follow-up before discussing strain details or proprietary process information.
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